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Treatment with FP2 in HeLa cancer tumors cells demonstrated anti-proliferation impact and up-regulated the expression levels of caspase-3 and cleaved-PARP. IC50 values were 31.50 and 22.62 μg/ml for 24 h and 48 h, respectively. FP2 has prospective of antitumor possibly due to apoptosis induction mediated through caspase-3 activation and cleavage of PARP. The results suggest that FP2 can be a promising plant polysaccharide concentrating on for antic