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Cardiac myxomas are typical and account for 50% of primary intracardiac tumors. Atypical places of cardiac myxoma boost the risk of intraoperative iatrogenic injuries. Herein, we report an instance of utilizing three-dimensional publishing (3D) to facilitate the elimination of an atypical cardiac myxoma in a 63-year-old woman. Mass in the large posterior atrial septum was confirmed through imaging. Because of the possible involvement of the mass to surrounding important structu