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These patients are at extremely high threat of thrombosis as well as haemorrhage, plus the optimum handling of anticoagulation is challenging for the treatment of clinicians, particularly as powerful potential research is sparse. In this concentrated review, we discuss (1) danger factors for thrombosis and hemorrhaging in these patients, (2) handling of intense venous thromboembolism (VTE) including evidence for direct oral anticoagulants, and just how to approach customers with contr
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