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r during downhill running in the early post-operation phase, but this effect is lost in the longer term. This suggests that healing and neuromuscular adaptation occur over time and may also indicate a dampening of the effect of LET over time. (337 /350 words) LEVEL OF EVIDENCE Level II. Unicompartmental Knee Replacements (UKR) are being performed in patients with increasing demands and life expectancies withsurgical concerns that cemented fixation will not last. Cementless fixation may offer a solution, but the results in different age