https://gs-7977inhibitor.com/a....tomic-family-genes-c
Our outcomes show that the binding of dopamine to its receptor is in keeping with the membrane-dependent binding and entry apparatus. Both experimental and simulation results showed that dopamine prefers binding to lipid membranes especially in the headgroup area. More over, our simulations unveiled a ligand-entry path from the membrane layer to the binding web site. This path passes through a lateral gate between transmembrane alpha-helices 5 and 6 in the membrane-facing region of the prot
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