https://www.selleckchem.com/pr....oducts/merbarone.htm
Neuromodulators regulate higher-order cognitive processes including learning and memory through modulation of synaptic transmission and plasticity. Norepinephrine is a neuromodulator that is secreted throughout the brain in response to novelty or increased arousal, which alters neural circuits by increasing the modifiability of CNS synapses. Norepinephrine activates metabotropic receptors, initiating complex intracellular signaling cascades that can promote enduring changes in synaptic strength including long-term potentiation (LTP).
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