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The Most Effective ADHD Medication For Adults Adults suffering from ADHD are typically prescribed stimulants. They aid in regulating levels of two chemical messages within the brain which control attention. The most effective adhd medication for adults is Strattera (atomoxetine). It comes as an oral capsule that can be taken with or without food. Many people find it to be efficient. It lasts longer than stimulants that have a shorter duration of action like amphetamine and methylpheni