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Degrees of bone ALP enhanced with increasing age (β 1.004, p less then 0.001), while female intercourse had no result. OC levels reduced with increasing age (β 0.998, p = 0.009) and increased with female sex (β 1.104, p less then 0.001). Considering our conclusions, we suggest for bone tissue ALP and OC three clinical RIs for males according to age and three clinical RI for females predicated on age and menopausal standing. CONCLUSION The RI for bon