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Opioid use disorder (OUD) treatment outcomes are poorer for young adults than older adults. Developmental differences are broadly implicated, but particular vulnerability factor interactions are poorly understood. This study sought to identify moderators of OUD relapse between age groups. This secondary analysis compared young adults (18-25) to older adults (26+) from a comparative effectiveness trial ("XBOT" that randomized (N = 57 participants to extended-release naltrexone or sublingual buprenorphine-naloxone. We explored the rel