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ocess. In the future, this may help target potential interventions to improve health span. We show wide variations between tissues in vulnerability to the aging process. In the future, this may help target potential interventions to improve health span.Isodicentric Y chromosome [idic(Y)] is one of the most common structural abnormalities of the Y chromosome and has been observed in patients with reproductive disorders and in patients with disorders of sexual development. Most idic(Y) chromosomes are found in mosaic form with a 45,X cell line. These