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Articular cartilage defects are one of several significant challenges in orthopedic and upheaval surgery. Nevertheless, the indegent capability of cartilage to self-repair has actually motivated efforts to engineer replacement cells, and human mesenchymal stem cells (MSC), which have a thorough proliferation possible and certainly will undergo chondrogenesis, have actually emerged as a promising mobile source. In this analysis, we try to supply a brief history of MSC
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