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What Happens If ADHD is Left Untreated in Adults? Adults suffering from ADHD may experience a variety of issues when the condition is not treated. These problems can affect work, relationships, and mental health. Many times, people who suffer from untreated ADHD have low self-esteem as well as a negative perception of the world. This can make them feel like failures at work and home. of Focus Having trouble staying focused from time to time is normal particularly after a long