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In UC group, the content of CRP, FSTL1 and D-dimer was significantly higher than that in the control group (P less then 0.05). The DAI score was significantly higher (P less then 0.05), the content of MMP-2 and MMP-9 was remarkably raised (P less then 0.05), the platelet count, PT, APTT and fibrinogen level were all obviously increased (P less then 0.05), and the L/M ratio was notably lower (P less then 0.05) in the UC group than in the control group. In patients with active UC, MMP-2, MMP-9 and inflammatory factors were significantly i