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Because of the rarity of PJS, this work together with earlier researches, have proved the significance of LKB1 promoter methylation in PJS development and prognosis.The promoter methylation level of LKB1 gene in PJS polyps is normally raised weighed against normal colon mucosa. However not every one of PJS polyps carry hypermethylated LKB1 promoter. Hypomethylation in this area has actually linked to cancerous tumors in PJS clients. Given the rareness
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