https://www.selleckchem.com/pr....oducts/Temsirolimus.
5-HT7R is confirmed as a pivotal therapeutic target for the recovery of neuronal function supporting the translational value of this promising pharmacological approach for RTT.A bidentate pyrazolylpyridine ligand (HL) was installed on divalent nickel to give [(HL)2Ni(NO3)]NO3. This compound reacts with a bis-silylated heterocycle, 1,4-bis-(trimethylsilyl)-1,4-diaza-2,5-cyclohexadiene (TMS2Pz) to simultaneously reduce one of the nitrate ligands and deprotonate one of the HL ligands, giving octahedral (HL)(L-)Ni(NO3). The mononitrate