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How Does ADHD Medication Work? ADHD is treated by taking stimulants. They regulate the levels of neurotransmitters (two brain chemicals) which transmit messages between neurons to improve attention and decrease excessive hyperactivity. However, as much as 20% of people do not respond to the most frequently prescribed stimulants, methylphenidate or amphetamine. This could be due to the chemistry of the body of the individual or other medications that they are taking. What are the symptoms of ADHD?
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