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ADHD Stimulant Medication Stimulants help about 70% to 80% of children and adults suffering from ADHD. They reduce symptoms by increasing dopamine and norepinephrine levels. The effects of these medications begin to take effect in 30 to 45 minutes, and last between 3 and 6 hours. The medicines are available in liquid or chewable tablet form. Nonstimulant medications can be prescribed by your doctor to help you take stimulants in conjunction. These include the drugs atomoxetine (Stratt