https://www.selleckchem.com/pr....oducts/lomerizine-hc
We established a semi-high-throughput in vivo screening platform using hyperactive piggyBac (hyP transposons (designated as PB-miR) to identify microRNAs (miRs) that inhibit hepatocellular carcinoma (HCC) development in vivo, following miR overexpression in hepatocytes. PB-miRs encoding six different miRs from the miR-17-92 cluster and nine miRs from outside this cluster were transfected into mouse livers that were chemically induced to develop HCC. In this slow-onset HCC model, miR-20a significantly inhibited HCC. Next, we dev
Like
Comment
Share
