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ngineered carbon based nanoparticles with environmental and occupational health relevance. Inflammatory mediators in sera from CBPs may bridge carbon black exposure and endothelial cell activation response assessed ex vivo. CBPs may have elevated risk for cardiovascular diseases when comorbidity exists. Our study may serve as a benchmark for understanding health effects of engineered carbon based nanoparticles with environmental and occupational health relevance. Illicit drug use increases visits to the hospital. Research is limited on