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01). Three or fewer IDRFs prior to surgery was associated with the highest odds ratio for 90% GTR at 9.33 [95% confidence interval 3.14-31.5]. Neoadjuvant chemotherapy reduced the number of IDRFs in the majority of patients with high-risk neuroblastoma. The number of IDRFs present after neoadjuvant therapy correlated with the extent of resection. Neoadjuvant chemotherapy reduced the number of IDRFs in the majority of patients with high-risk neuroblastoma. The number of IDRFs present after neoadjuvant therapy correlated with the ext