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Together with prior studies, the results support the possible influence of sialic acid O-acetylation and O-acetyl migration to host-microbe interactions and potential application of the more stable synthetic N-acetyl mimics.Photocatalysis is an effective and environmentally friendly approach for degrading organic pollutants, particularly in scenarios where sunlight can be utilized as the energy source. Opportunities are emerging to apply materials and methods from photocatalytic pollutant degradation to address the challenge of fouling.