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d the polar head of SDS contributes to the solubilization of butyl methacrylate. The different submicellar solubilization mechanisms are mainly caused by the different properties of solutes and surfactants, which also results in different MSRs and solubilization sites in the micelles.Techniques for immobilization and release of proteins are of general interest but challenging to develop. Here we show a new method for high-capacity (several μg cm-2) immobilization of proteins in polyelectrolyte brushes by multivalent hydrogen bonds. Upon