https://bms-754807inhibitor.co....m/development-of-a-f
Recently, programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) checkpoint blockades have now been applied for GBM treatment. Nonetheless, the device of PD-L1 upregulation in GBM remains ambiguous. COP9 signalosome 6 (CSN6) is a must for maintaining the necessary protein stabilization in disease cells. In this research, we used personal GBM specimens and cell outlines to analyze if the EGFR-ERK pathway regulates CSN6 for PD-L1 upregulation. Data throu
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