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Numerical simulations showed that the TVE were 1.6±2.7% and 1.3±2.2%, the average absolute differences in tumor motion amplitude were 0.3±0.7mm and 0.3±0.6mm, and the ADM were 4.1±0.9% and 3.5±0.9% for irregular and regular breathing, respectively. The SNR of the T and T maps of the liver and the tumor were generally higher for regular breathing compared to irregular breathing, whereas tumor-to-liver contrast is similar between the two breathing patterns. The proposed technique was successfully implemented on the healthy volunteers. We ha