https://vs-6063inhibitor.com/c....onnection-of-hydroxy
Present information implies that LARP4 opposes deadenylation by stabilizing PABP on mRNA poly(A) tails. Various other data claim that LARP1 can protect mRNA from deadenylation. This is certainly influenced by a PAM2 motif with exclusive characteristics present in its La-module. Hence, while atomic Los Angeles and LARP7 stabilize little RNAs with 3' oligU) from decay, LARP1 and LARP4 bind and protect mRNA 3' poly(A) tails from deadenylases through close contact with PABP.
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