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- Choosing the Right One Medicines can be an essential part of treatment for ADHD. Different medications affect people in different ways and determining the best one may take time. Stimulants boost the levels of brain chemicals that aid concentration and control of impulses. They can also trigger adverse effects such as shaking hands, stomach discomfort and an increase in heart rate. Stimulants Stimulants are substances that "stimulate" brain processes and activit