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Coordinated assembly of viral and host factors is essential for the successful propagation of viruses as well as the generation of host anti-viral response. Previous studies from our group, as well as from other groups, have identified host proteins interacting with various components of the Hepatitis E virus (HEV). However, the functional relevance of host protein interactions in HEV replication context has been notably overlooked. The present study reports that heterogeneous nuclear ribonucleoproteins (hnRNPs), namely hnRNPK, hnRNPA2B1
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