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0-118.1] MME vs 17.9[3.5-48.8] MME vs 8.8[2.1-25.0] MME, p 0.001). Twenty-six percent (n = 35) of all patients were opioid users beyond 180days postoperatively. Variables associated with opioid use 180days were chronic preoperative opioid use (OR 23.8, p 0.01), daily inpatient opioid requirement (1.02, p 0.01), and neoadjuvant chemotherapy (28.2, p 0.01). A quarter of patients are opioid dependent after lung cancer resection. This is due to both preexisting and new persistent opioid use. Improved strategies are