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Introduction The present study aims to assess the microshear bond strength (µSBS) of composite to enamel treated with titanium tetrafluoride (TiF4 ) and CO2 laser irradiation. Methods Fifteen human molars were sectioned and their enamel surfaces were abraded. The sections were randomly assigned to 5 groups (n=15) (CO); control group, (AP); treated with 1.23% acidulated phosphate fluoride (APF) for 4 minutes, (Ti); 4% TiF4 for 1 minute, (L+AP); CO2 laser irradiation (10.6 µm wavelength, 1 W peak power, 10 ms pulse duration, 500 ms repet
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