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111, P = 0.046). CONCLUSIONS Stereotactic body radiation therapy was an excellent ablative treatment option for patients with small HCC. Tumor size was a significant factor for local tumor control after SBRT, although the total dose was negatively correlated with tumor size. Considering the low OS rates and the high local tumor control rates, the combined SBRT and systemic therapies may be beneficial for improving survival outcomes. © 2020 Journal of Gastroenterology and Hepatology Foundation and John Wiley Sons Australia, Ltd.Hepatitis A Virus (HAV)