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Forty-five Sprague-Dawley rats were randomized to 3 groups. Thirty rats received a vein graft procedure, and additionally they had been randomized is addressed with vehicle or atorvastatin; fifteen rats obtained a sham procedure. We detected intimal hyperplasia by hematoxylin-eosin staining and relevant protein expression by immunohistochemical and Western blot evaluation. Reviews were examined by single-factor evaluation of variance and Fisher's least factor test, with p 0.05 consi