https://www.selleckchem.com/pr....oducts/k-ras-g12c-in
Ratiometric reporters are tools to dynamically measure the relative abundance of a protein of interest. In these systems, a target protein fused to a fluorescent or bioluminescent reporter is expressed with fixed stoichiometry to a reference protein fused to a second reporter. Both fusion proteins are encoded on a single transcript but are separated during translation by a 2A "self-cleaving" peptide. This approach enables changes in the relative abundance of a target protein to be detected sensitively, reducing variability
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