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05). A significant deterioration of meibomian gland parameters was observed in AC group when compared with control subjects, demonstrated by severe upper and lower MGL, lid margin abnormalities, decreased meibum expressibility, and abnormal meibum quality, all of which were worse in the severe type of AC (all P 0.05). Thinner LLT was significantly correlated with decreased TBUT (β = 3.666, P 0.001) and severity of upper MGL (β = - 7.701, P = 0.002). Decreased LLT and blinking disorders in pediatric patients with AC may contrib