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To review the research progress of bioreactor (IV for bone tissue engineering in order to provide reference for its future research direction. The literature related to IVB used in bone tissue engineering in recent years was reviewed, and the principles of IVB construction, tissue types, sites, and methods of IVB construction, as well as the advantages of IVB used in bone tissue engineering were summarized. IVB takes advantage of the body's ability to regenerate itself, using the body as a bioreactor to regenerate new tissues or organ