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Finding the Best ADHD Medication For Adults There are many ways to treat ADHD in adults. There are stimulants, nonstimulants, and blood pressure medicines. are the most frequently prescribed medication for ADHD. They are effective and safe. They also pose a low risk for abuse when taken as directed. Long-acting stimulants are generally preferred. These are medicines like Xelstrym (dextroamphetamine/amphetamine patch) or Mydayis (lisdexamfetamine). 1. Stimulants Stimulants are typically the first choice of a doctor's medication to treat ADHD. T