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3% vs 6.0% in physicians; p0.001) and organisational activities (20.4% vs 9.5%; p0.001). Overall mean interruption rate per hour was 10.16 (US ED 8.15, German ED 12.04; p0.001). American physicians and German nurses were most often disrupted by colleagues of the same profession (country B=-.27, p=0.027; profession B=0.35, p=0.006). German ED staff were interrupted more often by patients (B=-.78, p=0.001) and other sources (B=-.76, p0.001) than American ED staff. Our findings corroborate that profess