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Medication For ADHD - What Are the Side Effects? Many people who suffer from ADHD experience a reduction in symptoms when they use medication. Each person's reaction to drugs is different, and the side effects can be problematic. Methylphenidate is part of a group of drugs known as stimulants. It increases the levels of a chemical in the brain that helps regulate behavior and attention. Stimulant medication Stimulant drugs improve attention and concentration in 70 to 80percent of children