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Translational PAI also attracted growing interest in clinical applications including tumor margin examination, internal organ imaging, breast cancer screening, and sentinel lymph node mapping, among others.Label-free intravital optical imaging is an emergent visualization tool that is not only useful for basic biological research, but also for preclinical research with potential translational clinical applications. The complete absence of exogenous labeling or genetic alterations avoids plausible harmful perturbation to biological proce