https://www.selleckchem.com/pr....oducts/gsk591-epz015
Key points• Fundamental properties of various ribose-5-phosphate isomerases (Rpis).• Differences in crystal structure and catalytic mechanism between RpiA and RpiB.• Application of Rpi as a rare sugar producer and a potential drug target.Background Administration of diuretics and the presence of ascites in patients with cirrhosis were reported to be associated with muscle cramps; however, the clinical evidence is limited. This study aimed to determine whether muscle cramps are a diuretic-induced complication and whet
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