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Its lack has previously been proven to result in increased obesity in mice on a top fat diet. The goal of this study would be to determine ways that properdin plays a role in a less pronounced overweight phenotype. Materials and techniques crazy type (WT) and properdin lacking mice (KO) had been provided a high-fat diet (HFD) for as much as 12 days. Outcomes There was an important increase in liver triglyceride content within the KO HFD team compared to WT on HFD. WT developed steatosis.
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