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How Does Medication For ADHD Work? Stimulants increase levels of dopamine and norepinephrine in your brain, assisting in improving concentration and impulse control. They are available in both immediate-release (short acting) and extended release tablets. They are taken every day in the morning. Nonstimulant medicines are more difficult to use but they can improve attention and impulse control. Atomoxetine, Viloxazine and guanfacine are antidepressants that boost norepinephrine levels. Stimulants The