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Proton MRI is the sole imaging technique that can show structural and functional lung changes in one examination. Structured assessment using ascoring system helps to systematically grade the extent and severity of all CF-associated changes. Lung MRI for cystic fibrosis has been recently established as aclinical standard examination and is routinely performed at experienced centers. More recently, it has also been used as an endpoint within the framework of clinical studies. Lung MRI for cystic fibrosis has been recently established as