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When physician diagnosis was used as a gold standard, PPV was 90.6% (95% confidence interval [CI] 87.7-93.5). PPV with expert adjudication was also 90.6% (95% CI 87.7-93.5). PPVs with enrollment in the IDR as gold standard were lower at 41.5% (95% CI 36.6-46.3) due to incomplete case registration. The claims-based algorithm developed for use in Japan is likely to identify UC cases with high PPV for clinical studies using administrative claims databases. The claims-based algorithm developed for use in Japan is likely to identify UC cases