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The 3 phenolamides revealed low to modest anti-bacterial tasks but had the ability to counteract the LPS pro-inflammatory impact on THP-1 cells classified into macrophages. Extracts made of healthier but not T. absoluta-infested tomato leaf extracts had been also able to reduce irritation utilizing the same cellular method. Taken together, these results reveal that phenolamides from tomato leaves might be interesting choices to mainstream drugs.In this research,