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SUMO features a vital role when you look at the signaling pathway governing type I interferon (IFN) production, and one of the SUMOylation substrates tend to be numerous IFN-induced proteins. The general effect of IFN is increasing international SUMOylation, pointing to SUMO within the antiviral stress response. Viral representatives allow us different mechanisms to counteract the antiviral activities exerted by SUMO, plus some viruses have developed to exploit the ho