https://tie-2signaling.com/ind....ex.php/extensive-pat
OBJECTIVES To characterize the pharmacokinetics (PK) of intravenous voriconazole (VRC) in critically ill clients with liver dysfunction. TECHNIQUES Patients with liver dysfunction into the intensive attention device (ICU) had been prospectively included. The Child-Pugh (C-P) rating had been utilized to classify the amount of liver disorder. The first intravenous VRC dosing regimen composed of a loading dose of 300 mg q12 h for the first 24 h followed by 200 mg q12 h. The very