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RESULTS In durations of 1973-1977and2008-2013, the age-standardized prices of LC occurrence and mortality (per 100 000 persons) are 24.27 and 22.60 in guys, 7.50 and 7.26 in females, respectively. The decreasing styles of LC incidence and death prices had been seen, for both sexes (AAPC, P less then 0.05 for many). The suitable of APC designs indicated that LC rates of occurrence and death had been dramatically influenced by both calendar time and birth cohort effects. CONCLUSIONS frequency and death r