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The purpose of this research was to identify predictors of pressure injury, using data from the electronic health records of critically ill adults. A retrospective cohort study was conducted using logistic regression models to examine risk factors adjusted for age, gender, race/ethnicity and length of stay. The study cohort included 1587 adults in intensive care units within an urban academic medical centre. The presence or absence of a hospital-acquired pressure injury was determined during monthly skin integrity prevalence surveys. All