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ADHD Medications For Adults Stimulants help adjust levels of chemical messengers in the brain that regulate attention. They are first-line medications for treating ADHD. They aren't considered to be habit-forming, however they can have side effects, such as headaches and difficulty sleeping. Your doctor could prescribe Guanfacine (brand names Tenex and Intuniv) or Clonidine (Catapres) to decrease the impulsivity and hyperactivity. These drugs have a longer duration of action than