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All substances had been evaluated with regards to their inhibitory results from the nitric oxide (NO) manufacturing caused by lipopolysaccharide (LPS) in murine RAW264.7 macrophage cells. Substances 2, 5, 6 and 9 exhibited moderate inhibitory activity with IC50 values when you look at the array of 17.4-26.5 μM, being stronger as compared to positive control dexamethasone (IC50 = 32.5 μM). FACTOR We desired to evaluate the connection of reports of discrimination with leukocyte telomere length (LTL) and impact measure modification